[REC]²

An ex-cop and his family are the target of an evil force that is using mirrors as a gateway into their home.

After failing to kill stubborn survivor Laurie and taking a bullet or six from former psychiatrist Dr. Sam Loomis, Michael Myers has followed Laurie to the Haddonfield Memorial Hospital, where she's been admitted for Myers' attempt on her life. The institution proves to be particularly suited to serial killers, however, as Myers cuts, stabs and slashes his way through hospital staff to reach his favorite victim.

Cocky researcher Sebastian Caine is working on a project to make living creatures invisible. Determined to achieve the ultimate breakthrough, Caine pushes his team to move to the next phase — using himself as the subject. The test is a success, but when the process can't be reversed and Caine seems doomed to future without flesh, he starts to turn increasingly dangerous.

Following Jigsaw's grisly demise, Detective Mark Hoffman is commended as a hero, but Agent Strahm is suspicious, and delves into Hoffman's past. Meanwhile, another group of people are put through a series of gruesome tests.