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After witnessing a bizarre, traumatic incident involving a patient, Dr. Rose Cotter starts experiencing frightening occurrences that she can't explain.

Ebony Jackson, a struggling single mother fighting her personal demons, moves her family into a new home for a fresh start. But when strange occurrences inside the home raise the suspicions of Child Protective Services and threaten to tear the family apart, Ebony soon finds herself locked in a battle for her life and the souls of her children.

When an unknown disease wipes out most of the world’s population, a man with unique blood is isolated for study. Fearing for his wife’s safety, he breaks his quarantine – into a world overrun by monstrous Infected and a shadowy agency hunting them down.

An Oxford Medical School graduate takes a position at a mental institution and soon becomes obsessed with a female mental patient, but he has no idea of a recent and horrifying staffing change.