Panhandle 38

Renowned gunman Richard Martin is traveling on a train, held up by Billy Kane, a former student of Martin's. Kane spares Martin, but only after shooting his hands. Years later, Martin meets an escaped convict, wrongly convicted for the train robbery. Martin trains his new student and both men seek out Billy Kane.

History Professor Brad Fletcher heads west for his health, but falls in with Solomon Bennett's outlaw gang. Fascinated by their way of life, Fletcher finally takes over the gang, leading with a new 'efficient' ruthlessness.

Wily roving gunslinger Sartana arrives in a small town and tries to find a hidden fortune of half a million dollars in gold and two million dollars in counterfeit money. Naturally, a bunch of other treacherous folks who include conniving widow Senora Manassas, shrewd fellow gunslinger Grand Full, and the vicious and unhinged General Monk are also looking to get their greedy hands on said fortune.

The Mexican guerilla leader Tepepa and his gang fight against the chief of police, Cascorro.