Misiones, 1756

While moving a group of Apaches to a Native American reservation in Arizona, an American scout named Sam Varner is surprised to find a white woman, Sarah Carver, living with the tribe. When Sam learns that she was taken captive by an Indian named Salvaje ten years ago, he attempts to escort Sarah and her half-Native American son to his home in New Mexico. However, it soon becomes clear that Salvaje is hot on their trail.

After crossing the border illegally for work, Miguel, a hard-working father and devoted husband, finds himself wrongfully accused of murdering a former sheriff’s wife. After learning of his imprisonment, Miguel’s pregnant wife tries to come to his aid and lands in the hands of corrupt coyotes who hold her for ransom. Dissatisfied with the police department’s investigation, the former sheriff tries to uncover the truth about his wife’s death and discovers disturbing evidence that will destroy one family’s future, or tear another’s apart.

A man in search of revenge infiltrates a ranch, hidden in an inhospitable region, where its owner, Altar Keane, gives shelter to outlaws fleeing from the law in exchange for a price.

When the South loses the war, Confederate veteran O'Meara goes West, joins the Sioux, takes a wife and refuses to be an American but he must choose a side when the Sioux go to war against the U.S. Army.