Ternitz, Tennessee

When seventeen-year-old Hannah stumbles upon a website about Thinspiration--an online community devoted to anorexia as a life choice--she becomes an obsessive follower of the site founder, ButterflyAna. By the time Hannah's family realizes what is happening and get Hannah the help she needs, the disease has fully taken hold and Hannah is refusing to eat. Will this family be able to exorcise the demon of anorexia from their lives?

In a suburban landscape, the lives of several families interlace with loss, despair and personal crisis. Esther Gold has lost focus on all but caring for her comatose son, Paul, and neglects her daughter and husband. Lawyer Jim Train is devoted to his career, not his family. Helen Christianson wants to find a new spark in life, while Annette Jennings tries to rebuild hers.

In East Los Angeles, an 18-year-old struggles between her ambitions of going to college and the desires of her domineering mother for her to get married, have children, and oversee the small, rundown family-owned textile factory.

A poor, struggling South Carolinian mother and daughter face painful choices with their resolve and pride. Bone, the eldest daughter, and Anney her tired mother, grow both closer and farther apart: Anney sees Glen as her last chance.