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In Venice Beach, naive Midwesterner JB bonds with local slacker KG and they form the rock band Tenacious D. Setting out to become the world's greatest band is no easy feat, so they set out to steal what could be the answer to their prayers... a magical guitar pick housed in a rock-and-roll museum some 300 miles away.

When a couple discovers that a brass teapot makes them money whenever they hurt themselves, they must come to terms with how far they are willing to go.

Two former backup soul singers, Louis and Floyd, have not spoken to each other in 20 years, and reluctantly agree to travel across the country together to a reunion concert to honor their recently-deceased lead singer. Cleo, a beautiful young woman who is believed to be Floyd's daughter, accompanies them as a new singer.

Count Dracula returns to the world of humans accompanied by Frankenstein's Monster, the Wolfman, the Mummy, and the Gillman. The uglies are in search of a powerful amulet that will grant them the ability to rule the world. A group of horror-loving heroes are the only ones daring to stand in their way.