Twitch and Shout

They blink, they grimace, they jerk, they moan. No matter how hard they try, their bodies, minds, and voices won't do what they're told. People with Tourette Syndrome (TS) , a rare and incurable genetic disorder, are the subject of the irreverently titled Twitch and Shout, a riveting, unsettling, and frequently funny inside look at what it's like to live with this often misunderstood neurological condition. Twitch and Shout not only sheds light on the nature of this puzzling disorder, it also examines the way society all too often heaps scorn and abuse on those who stray, however involuntarily, outside the limits of conventional behavior.

Directed by Laurel Chiten, Twitch and Shout leans on a strong ensemble — Lowell Handler, Evan Handler — to carry a story that balances spectacle with character.

The film landed with audiences for its craft and performances, and remains one of the most talked-about documentary titles of 1995.