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Will Truman and Grace Adler are best friends living in New York, and when Grace's engagement falls apart, she moves in with Will. Together, along with their friends, they go through the trials of dating, sex, relationships and their careers, butting heads at times but ultimately supporting one another while exchanging plenty of witty banter along the way.

Jessica Day is an offbeat and adorable girl in her late 20s who, after a bad breakup, moves in with three single guys. Goofy, positive, vulnerable and honest to a fault, Jess has faith in people, even when she shouldn't. Although she's dorky and awkward, she's comfortable in her own skin. More prone to friendships with women, she's not used to hanging with the boys—especially at home.

Six young people from New York City, on their own and struggling to survive in the real world, find the companionship, comfort and support they get from each other to be the perfect antidote to the pressures of life.

Rules of Engagement is a comedy about the different phases of male/female relationships, as seen through the eyes of a newly engaged couple, Adam and Jennifer, a long-time married pair, Jeff and Audrey, and a single guy on the prowl, Russell. As they find out, the often confusing stages of a relationship can seem like being on a roller coaster. People can describe the ride to you, but to really know what it's like you have to experience it for yourself.