Welcome to the El-Palacio

Banri Tada is a freshman at a Tokyo law school. After an accident, he suffers severe memory loss. Despite the incident, he befriends fellow freshman, Mitsuo Yanagisawa, which leads him to the beautiful, yet obsessive, Kouko Kaga.

At first, Takayuki Narumi is befriended by Mitsuki Hayase only because Mitsuki's best friend, Haruka Suzumiya has a crush on him; however since then, Takayuki, his pal Shinji Taira, and Mitsuki have grown to be the best of friends. Then one day, Haruka confesses to Takayuki her love for him. Not wanting to hurt her feelings, Takayuki agrees to go out with her. After a few incidents, their relationship gets intimate, even while Takayuki and Mitsuki begin to realize their feelings for each other. But suddenly, when tragedy strikes, things are never the same for these four friends again.

After her mother took the blame for a tragic fire 13 years ago, Anzu plots revenge by working as a housekeeper under a pseudonym for her icy stepmother.

On Christmas Eve, Hiro Hirono meets a girl named Miyako Miyamura as she chases a purse snatcher. Hiro later finds out that Miyako also goes to the same school as he does and they start hanging out together. This makes Hiro's childhood friend, Kei Shindō, feel left out, so she tries to compete with Miyako for Hiro's affection, creating a love triangle. Meanwhile, Renji Asō meets a girl named Chihiro Shindō at an abandoned train station. He soon learns that Chihiro suffers from a type of amnesia where her memory lasts for only 13 hours. He also discovers Chihiro's dream of writing a novel, but she has never been able to fulfill that dream due to her condition. Renji then decides to help her fulfill that dream.

17 years ago, immortals first appeared on the battlefields of Africa. Later, rare, unknown new immortal lifeforms began appearing among humans, and they became known as "Ajin" (demi-humans). Just before summer vacation, a Japanese high school student is instantly killed in a traffic accident on his way home from school. However, he is revived, and a price is placed on his head. Thus begins a boy's life on the run from all of humankind.

Yuki Itose is just a typical student dealing with the pressures of college. She is struggling one day on the train when an upperclassman named Itsuomi Nagi helps her out. As he gradually opens a new world to her, Yuki develops feelings for Itsuomi. A pure love story begins to grow.