Blade of the Immortal

Spurred by the flame raging in his heart, the Black Swordsman Guts continues his seemingly endless quest for revenge. Standing in his path are heinous outlaws, delusional evil spirits, and a devout child of god. Even as it chips away at his life, Guts continues to fight his enemies, who wield repulsive and inhumane power, with nary but his body and sword—his strength as a human.

Ginko, a Mushi master, travels from place to place researching the Mushi and helping people who are suffering because of it.

When lone swordsman Guts is defeated in a duel by Griffith, ambitious leader of the Band of the Hawk mercenaries, he now must fight for him. Distrustful of all at first, through hard-fought battles, he soon begins to bond with his new comrades and their leader. As they rise in rank to a full-fledged army, he begins to harbor doubts about a life lived by the blade, unaware a dreadful fate that awaits.

Yukimura Chizuru is the daughter of a doctor who works in Edo; her father leaves Edo to work as a volunteer doctor and moves to Kyoto without his daughter. As time passes by, Chizuru starts worrying about losing contact with her father, so she decides to go to Kyoto in search of him. On the way, Chizuru is attacked by few criminals and witnesses a fight between an oni and the Shinsengumi. Taking her into custody and saving her, the Shinsengumi debate on what to do with Chizuru when they discover that she is the daughter of the doctor they are also looking for. So they decide to become Chizuru's protectors and help her look for her father (the doctor). Lots of events happen while she stays with the Shinsengumi, as they discover mysterious secrets and also fight against the Bakumatsu group.