Hard-working Dave loves Grace, but she rejects him for a flashier suitor. Grace is blinded in an accident, and her suitor abandons her. Meanwhile, Dave also goes blind from eye strain caused by overwork. Dave learns of Grace's misfortune and gives a doctor the money he was saving for his own operation, so her sight can be restored.

A young woman reads tales of a gallant White Knight and imagines that such a knight might come to rescue her from her dull existence. Although she is wooed by a wealthy industrialist, she rejects his suit in hopes that her romantic ideal might come. One day a young writer comes to her village, and it seems as if he might be the hoped-for White Knight.

On a whim, a greedy tycoon decides to corner the world market in wheat. This doubles the price of bread, forcing grain producers into charity lines and others further into poverty. The film contrasts the differences between the lives of those who work to grow the wheat and the life of the man who dabbles in its sale for profit.

The physician's death orphans his two adolescent daughters. Their older brother is able to convert some of the doctor's small estate to cash. But it is late in the day, and with the banks closed he stores the money in his father's household safe. The slatternly housekeeper, aware of the money, enlists a criminal acquaintance to crack the safe. She attempts to get into the adjacent room where the sisters tremble in fear, but finds that the door is locked. The drunken housekeeper menaces them by brandishing a gun through a hole in the wall.

Poor Hiram didn't anticipate the trouble laid out for him when he and his wife went for a stroll in the park.

The young son of a wealthy Mexican house returns home from school. He is the only son of a widowed mother, whose heart beats only for him. He becomes fascinated by a pretty but low barmaid, who really returns his love, he being the first person she has truly loved.

A man loses his business and his fiancée, and drifts into the saloons. There he meets a similarly-downtrodden young woman. She works behind the scenes to help him recover his life, and eventually he realizes how steadfast she is.

A blind princess is informed that her sight can be restored by the first kiss of unselfish love she receives. She remains blind until a humble poet steals a kiss.

Two sisters, Nellie and Florence, support themselves and their mother by sewing. A man accompanying a wealthy client tempts first Nellie and then Florence to leave with him. Nellie rejects him, but Florence goes to his decadent apartment and becomes his mistress. Nellie marries a diligent carpenter and raises a growing family. Eventually the Tempter tosses Florence out, and she dies alone and impoverished.

Marta asks her husband Jose to buy her a new dress she saw at the market. On his way home, he goes with a friend to a saloon and drunkenly gives the dress to a barmaid. At home Jose tells his wife he lost the dress. She retraces his steps and finds the barmaid modeling her new dress. Faced with the truth, she goes mad.

Bobby is jealous of the new baby, so he takes it to the zoo and tries to return it to the stork.

A wealthy, callous moneylender finds a terrifying way to learn about money's limitations.

Before Tom departs for the city, he becomes engaged to Kate. She gives him half of her broken pendant cross, with the agreement that either can end the engagement by sending his or her half to the other. In a city boarding house, Tom is vamped by a flirtatious manicurist who learns of the agreement and sends Tom half a cross, pretending it is from Kate. Tom realizes he has been tricked and returns to the country and his fiancée.

With younger brothers and sisters to support, Peggy takes on the task-heavy job as maid for Mrs. Stuyvesant. Peggy also manages to help the woman's children, a lovelorn daughter and a son who is the unwilling tool of spies.

A young woman who is engaged to a millionaire she doesn't love meets and falls in love with a rough sailor.

A young girl working as a waitress at a resort for the wealthy is swept off her feet by a rich young gentleman who's there for the summer. However, his impending nuptials with another woman complicate the matter.

An experiment goes wrong and blinds a newly married chemist. The chemist's wife does not want to take on the burden of caring for the blind chemist, and her younger sister take her place.

Moving Picture World described the film: "There is a small need to describe this subject as the poem of Lord Tennyson is so well known, so suffice it to say that this Biograph subject is an unusually faithful portrayal of that beautiful romance of Enoch Arden, Annie Lee and Philip Ray, taken in scenes of rare beauty". This is the combined feature version of Enoch Arden Parts I and II.

When the suitor of the daughter of an apparently wealthy widow finds out that the oil stocks, in which her late husband's fortune is invested, are worthless, he finds the daughter less attractive. The widow's broker has a wealthy friend, who becomes very interested in the girl, although he is twice her age. He proposes marriage, believing that he can win her love through kindness. The girl, for her mother' sake accepts and they are married. Despite his great love he is unable to overcome the great difference in their ages, so he buys the worthless oil stock so that she may be independent, and he then leaves her to go back to his oil fields. His sacrifice arouses the girl's love and she follows him to tell him of her awakening.

A quarrelling couple are forced to quarantine together after the household maid becomes ill of an infectious disease.