Follow the lives of a group of teenagers living in the upscale, star-studded community of Beverly Hills, California and attending the fictitious West Beverly Hills High School and, subsequently, the fictitious California University after graduation.

Experiments in biological warfare have destroyed all but a few remnants of the human race. Alone in a lab, eight students work feverishly to create a vaccine before they are forced outside in search for food. It is then that the surviving scientists discover creatures mutated by the plague. Now they prepare to do battle against their worst fear: The Terror Within.