Bizarre things start happening in the little New Mexico town where UFOs were spotted in 1947. Cut to 1999, when a cute high-school student saves the life of a teenage waitress. Surrounded by cliques of clever, angst-filled classmates, the two form a bond that threatens the survival of a secret universe involving superhuman powers, a yen for hot sauce and an alien gene pool.

Powerful businessman Russ Duritz is self-absorbed and immersed in his work. But by the magic of the moon, he meets Rusty, a chubby, charming 8-year-old version of himself who can't believe he could turn out so badly – with no life and no dog. With Rusty's help, Russ is able to reconcile the person he used to dream of being with the man he's actually become.

A fateful night in 1959, four people die when the bus they are riding crashes. They continue as ghosts; their souls become eternally entwined to the life of a child born at the moment of their deaths as his guardians. Baby Thomas grows up to be a businessman who has memories of his playmates, but assumes they are products of his youthful imagination. When the ghosts realize they need Thomas' help to move on to the afterlife, they decide to make an appearance once more.

Jimmy is the kid everybody ignores and uses. One day, he gets into a freak accident. The only way for him to survive is a brain transplant. He gets the brain of Milt Appleday, a famous cartoon creator. And when he wakes up, he can see cartoons!

In Taft, California, 1981, Johnny (Fred Meyers) is a unassuming baseball hopeful who turned against his stern and demanding father (Joe Estevez) and beat him to death with a baseball bat on a baseball diamond field. 17 years later, Johnny is released from the local insane asylum and begins a killing spree, with his father's ghost as an umpire.