John Schuyler, a happily married lawyer, is appointed diplomat and sent to England. Due to an unfortunate accident, his wife and child can not come along with him. On the ship to England, Schuyler meets the notorious Vampire - a relentless gold digger who causes the moral degradation of those she seduces, first fascinating and then draining the very life from her victims.

James Wadsworth sets his sights on the lovely society girl Anna Dalton and determines to marry her. To achieve that goal, he follows her everywhere she goes, including on a ship to South America. He comes up with a plan to make her love him--he throws her overboard, follows her over the side and swims with her to a deserted island. His somewhat unorthodox method works and he wins over Anna, but problems arise when Richard Towne, Anna's fiancé who has been searching for her, finds the island and discovers the two.

When her lover deserts her, Gioconda Dianti seeks revenge by wrecking the lives of other men. When famous sculptor Lucio Settala meets her and asks her to pose for him, she sets out to ruin him. She captivates the artist with her charms, and he soon forgets his wife Silvia, their daughter Little Beata, and even his work. After Gioconda defies Silvia to take her husband back, Lucio shoots himself in a fit of desperation. Although Silvia nurses him back to health, Lucio soon returns to the enticing Gioconda. When Silvia's subsequent quarrel with Gioconda becomes a fight, Gioconda attempts to destroy Lucio's statue, but it falls on Silvia and is saved. Silvia, however, is crippled for life. Because of this, Lucio's sanity is affected and he becomes a raving maniac. Later, cast aside by her "man of the world," Gioconda also descends into madness. A lost film.