Following the adventures of a bunch of nobodies who get up to a whole lot of nothing in the fictional prairie town of Dog River, Saskatchewan, Corner Gas focuses on the life (or lack thereof) of Brent LeRoy, proprietor of a gas station that is the only stop for miles around and a hub of action on the Prairies.

Ace, a 12-year-old boy is new in middle school. His grandfather from Transylvania passes away at the ripe age of 99, and sends him his dog, Fang, to look after. Ace soon discovers that Fang is a vampire dog. Professor Warhol, a mad scientist and her bumbling assistant Frank, try to capture Fang to steal his DNA, in order to look young.