Following the adventures of a bunch of nobodies who get up to a whole lot of nothing in the fictional prairie town of Dog River, Saskatchewan, Corner Gas focuses on the life (or lack thereof) of Brent LeRoy, proprietor of a gas station that is the only stop for miles around and a hub of action on the Prairies.

Having finally secured her first assignment from her family's demolition business, Sam Walczak is sent to supervise the destruction of an apartment house, only to discover a group of tenants still living in the condemned building. One such tenant, Jimmy, tells Sam an urban legend about a serial murderer who used to live in the building and entomb his victims in the walls. What's worse, the dead are believed to still harass the residents to this day.

The Lunar Base Ark explores ore and unexpectedly is hit by a meteor shower and has severe damages. Colonel Gerard Brauchman sends the crewwoman Ava Cameron to repair a wing that is full of CO2. Dr. Lance Krauss warns that the gas may cause paranoia and hallucinations. Ava brings a sample of the meteor for analysis and Dr. Krauss finds that there are spores attached to the meteor. Ava accidentally cuts her finger in a sample but she hides the cut from the doctor. Soon Ava gets pregnant and delivers an alien offspring. However, neither Col. Brauchman nor Dr. Kraus believes in her words and they believe that Ava is delusional. The offspring bites the crewman Bruce Johns and the crew discovers that Bruce has been cloned by the alien. Soon they find how dangerous the clone is.

A recently orphaned 15-year-old who has moved to a small town to live with her uncle befriends a robotic canine with super strength, x-ray vision and the ability to talk and the pair take on a military complex, bullies, kidnappers, romance and the world.

Ace, a 12-year-old boy is new in middle school. His grandfather from Transylvania passes away at the ripe age of 99, and sends him his dog, Fang, to look after. Ace soon discovers that Fang is a vampire dog. Professor Warhol, a mad scientist and her bumbling assistant Frank, try to capture Fang to steal his DNA, in order to look young.

It’s been a few years, and there’s still not a lot going on 40 kilometers from nowhere. But that’s all about to change as the fine folks of Dog River, Saskatchewan face their biggest crisis ever. Brent and the gang discover that the town’s been badly mismanaged, leaving residents with little choice but to pack up and leave. As residents make one last rally to save Dog River as they know it, they discover a devious plan by a corporate chain that would change life for Dog Riverites forever.

Martha Barlow, a modern day outlaw, must reconcile her dark past after her teenage son commits a horrible crime.