When Doctor Andrea Fanti loses 12 years of memories from a brain injury, he finds himself adjusting to a world full of strangers.

Follows the lives of three families who live in a three-story building in a Roman neighbourhood.

Nadine is a French young woman. Fausto is an Italian young man trying to make it in Paris as a restaurant waiter. They accidentally meet at a five-star hotel. Both are fragile, alone and obsessed with the idea of an unattainable happiness. Their intense love is challenged by their own individual ambition and desperation.

Nadia is an apathetic 16-year-old girl with no friends of sorts, in or outside school. One day, she takes a walk with local no-good Brando, and the boy rapes her. From that moment on, Nadia's life changes forever.

Teo has a good job, a fiancee, a lover, no intention to assume any responsibility in his life. Meeting Emma, a blind woman, will upset his convictions.

Siblings Petra and Jure want to re-purpose their old lakeside house. To raise money for such a venture, they get involved in the search for a lost dog, hoping to get a substantial financial reward. They cross paths with the ruthless entrepreneur Nicola. When their plan turns sour, Christmas turns into a nightmare riddled with slaps and plot twists.

Max would have stayed on his lonely alp forever. Then this Yankee puts a flea in his ear and tells him that he can have any woman with an edelweiss. Max has an edelweiss. ...She lives in Rome and has the unusual name Maria. But unfortunately not only noble intentions. It's a matter of life and death. Max chooses Edelweiss and wins Maria as his wife. Everything looks like a happy ending, but Max finds himself in the far reaches of Siberia... He never wanted to go there. Not without Maria anyway, and in a deadly showdown Max follows her trail of blood... Nothing should be spared in this black slapstick. Certainly not love.

Marta works for a poll company, listening all day to other people's dreams while leading a cold and solitary life. Having just cut off a long relationship, she tries an online sex chat under an alias, meeting a man who begins to advance more and more audacious requests, until they decide to discover their respective identities.

A convicted terrorist out on parole meets a man she nearly murdered 15 years before, without recognizing him. He does so, but he chooses to keep quiet and spend time with her—desperate to understand the reasons behind her gesture.

Paolo, 40 years old, lives in a small Friulian town close to the north-eastern border. Unreliable and with a passion for good wine, he spends his days at the local tavern and stubbornly stalks his ex-wife.

Angela is a dedicated and sensitive carer. She is a widow. Her husband, as many other workers in the area, died from asbestos-related diseases. When the man responsible for the many deaths, now crippled, is hospitalised, she accepts his son’s offer to become his caregiver, hoping to take her revenge.

How will the Germans react to the armistice of the 8th of September 1943, due to which Italy betrays them and sides with the allied forces? This is the distressing questions that a group of 16 Italian - Greek Jews evacuated at The Meina Hotel ask themselves.

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