College student Lucy and her friends spend their vacation at her family's home in Hawaii, which includes her pet chimpanzee, Ben. However, when Ben contracts rabies after being bitten by a rabid animal, the group must fight for their lives in order to avoid the now-violent chimp.

With only three weeks left in his three-year contract, Sam Bell is eager to return to Earth. Stationed alone at a Moon-based facility with his computer assistant GERTY, an unexpected accident sets off a series of unsettling events that shake his isolation.

When bike courier Chris witnesses what looks like a murder, his first instinct is to cut and run. But when his curiosity draws him back in, he's soon embroiled in a world of corruption, political power, and illegal bike racing.