Loving husband Lino is on a mission: his wife, who works as a domestic in Milan, is missing and he's determined to find her. To do so, he enters Italy illegally and takes cover as one of the hundreds of Filipino migrant workers who make their way to Europe.

A poet hearkens back to his Philippine village after years abroad in Europe. Horrified to discover that the community has been buried under landslides, he wanders the countryside, reconnecting with friends, lovers, and family whose lives teeter on the brink of destruction.

Sam (Yul Servo), a former soldier unintentionally gets disturb in a robbery gone wrong. Escaping with the bag of stolen loot, he hides inside an abandoned mansion where he meets the mysterious young woman Latia (Julia Clarete), bathing nude inside the homes filthy pool. They begin a passionate and blazing affair even as the crime kingpin Johnny B (Dido dela Paz) and his armed men launch a desperate search for the money.

Pandanggo has three stories with parallel themes converging in one event, the Kasilonawan Festival in Obando: a career woman learning to dance tango who is torn between her dance partner and live-in partner has to choose the man who will satisfy her dream of raising a family; a wife whose wish to conceive a baby boy to make her husband happy brings her feet to the festival, but fate has other plans of bringing the child into her life; and a modern woman who, amidst her medical condition that might render her childless for the rest of her life, finds connection with an ancient lore about fertility.