While undergoing heart surgery, a man experiences a phenomenon called ‘anesthetic awareness’, which leaves him awake but paralyzed throughout the operation. As various obstacles present themselves, his wife must make life-altering decisions while wrestling with her own personal drama.

Ordinary single girl Amanda Pierce unexpectedly finds herself sharing an awesome Manhattan apartment with four sexy supermodels. Determined to bring Amanda into their world, the models give her the ultimate makeover. The plan works fabulously as Amanda connects with next door charmer Jim Winston. That is, until one night while spying on him, Amanda thinks she sees the man of her dreams committing a cold blooded crime.

J.W. Garrison, the head of a top-secret sub agency of the United Nations, discovers that a team of terrorists, led by the murderous Oliver Maxwell, plan on producing a bomb carrying an anthrax virus to be used in the United States. Garrison summons CIA agent Zack Hamilton who puts together a team of three beautiful women; CIA trainer Kim Taylor; photographer Victoria Carrera; and actress Eva Kirov to go to undercover as fashion models to infiltrate the terrorist organization to find the bomb before it can be used.

The film features American retailer Victoria's Secret regular model Frederique Van Der Wahl, joining Tyra Banks and other supermodels in the rainforest. It explores the beauty of the rainforest in Costa Rica, with proceeds from sales going to help preserve the rainforest.