In Tree Hill, North Carolina two half brothers share a last name and nothing else. Brooding, blue-collar Lucas is a talented street-side basketball player, but his skills are appreciated only by his friends at the river court. Popular, affluent Nathan basks in the hero-worship of the town, as the star of his high school team. And both boys are the son of former college ball player Dan Scott whose long ago choice to abandon Lucas and his mother Karen, will haunt him long into his life with wife Deb and their son Nathan.

Nick Hume is a mild-mannered executive with a perfect life, until one gruesome night he witnesses something that changes him forever. Transformed by grief, Hume eventually comes to the disturbing conclusion that no length is too great when protecting his family.

A group of talented but rebellious 'rock-star scientists' find themselves in a race against time to save Earth when a comet makes an unexpected turn towards our blue planet where all life may cease to exist within days if our small town heroes fail to find a solution.

TV stars, pro athletes, ex addicts, and two racist hicks from the South end up under one roof in a botched extortion attempt.