With ruin staring him in the face, Manning, of Manning and Company, commits a theft which averts the crash. The scoundrel cleverly contrives to throw suspicion upon Reynolds, an old and faithful employee. Reynolds receives a three-year sentence. Beatrice, the daughter of Manning's victim, believes in her father's innocence. Led to believe Manning the real cause of her father's tribulations, Beatrice vows to wreak vengeance upon the scoundrel.

Kentucky moonshiner, Bill Evans lives with his family in the back hills. His daughter Mary marries another moonshiner, Jack Keane, which angers Bill Gale. The plot involves a love triangle and family conflict stemming from the moonshining life.

John spies his girlfriend embracing his brother. Stunned, John deposits the family's money and leaves the country. Years later he returns to find his brother dead, the plantation in ruins, and that he is suspected of stealing the money.

A man fights for this life in the Canadian Northwest.

Blake, a quarrelsome lineman, and a widower with two daughters, is in love with Helen, but she rejects his advances. Helen spies Myra, Blake's three year old daughter, who has ventured onto the tracks of the oncoming Elwood Express, and just in the nick of time, grasps the girl off the tracks, but in so doing, must leap off a trestle into a river thirty feet below

A pair of crooks steal a valuable package, hold up the crew of a freight engine, and compel the engineer to aid their escape. Learning this, Helen climbs into the cab of a locomotive standing on a siding and takes up the chase.

Blake, fireman of a light engine, receives a message that his wife is dangerously ill. Benton, his engineer, allows Blake to catch an eastbound passenger train. A hunter shooting as the light engine is passing, wounds Benton who drops unconscious. The sportsman reports the accident. Helen, a telegrapher, receives word of the runaway train. Climbing into the cab of a locomotive in a siding, Helen jerks the throttle wide open. The engine rushes after the endangered express. Discovering his train is being pursued, the conductor of the Eastbound Express gives the signal to stop. Helen slows her engine down and tells of the danger. While the Eastbound locomotive goes to meet the runaway, Helen's engine draws the cars to safety. The runaway is halted in the nick of time. Helen's superb heroism results in her being showered with offers of marriage. But she enjoys her hazardous adventure too much to marry anyone yet. —Moving Picture World synopsis

Helen, the telegrapher at Downing Junction, receives word that an engineer has been accidentally shot by a partridge hunter, and the runaway train will collide with the Eastbound Express. Helen jumps onto a nearby standing locomotive, opens it up full throttle, catches up the Express, warns the engineer of the impending danger

Harry Larrabee, a young playwright, lives in the same studio apartment house with Carolyn Vaughn, a painter of miniatures, with whom he falls in love. "The Wolf," a famous criminal, supposed to be dead, returns and communicates with his wife, a friend of Carolyn's. He forces his wife and her brother to aid him in a plot to rob Carolyn of her valuable jewels. Harry, by one of his famous "inspirations," discovers that a crime is being committed, rescues Carolyn and bears her away in a taxicab. He is himself suspected of the crime, but, undisturbed by the web of circumstance by which he is entangled, his wonderful inspirations give him the key to the conspiracy which led up to the crime. In an unusual and powerful finale the guilty parties fight among themselves and justice triumphs in an exciting climax.

Through the efforts of the Rev. John Drummond, who comes to a small western mining town with his little boy, all the saloons are closed. Jim Howe and his daughter, Nell, being unable to carry on a liquor business in the town, move to the mountains, where he runs an illicit still and continues to supply whiskey to the Indians. The sheriff gets on his trail and he is soon placed in the custody of the law. Nell, determining to avenge herself for the capture of her father, fires n shot into a party of hostile Indians, secreting herself in a bush as she does so. The Indians, seeing the soldiers coming, and thinking that they fired the shot, rush at them, but are defeated. This plan of revenge having failed, she makes her way to the minister's home, but is prevented from doing any harm to him by the maternal instinct which rises in her when she sees his little boy praying for his mother in heaven.

The Hazards of Helen is an American melodramatic adventure film serial of 119 twelve-minute episodes released between November 7, 1914 and February 24, 1917. Most episodes of this serial are presumed lost.

In the second entry of the popular Hazards of Helen series, Helen, is temporarily assigned as a telegraph operator at Quarry Depot; bad blood springs up between two men who are seeking Helen's favor, but to whom she has remained impartial.