In cases ripped from the headlines, police investigate serious and often deadly crimes, weighing the evidence and questioning the suspects until someone is taken into custody. The district attorney's office then builds a case to convict the perpetrator by proving the person guilty beyond a reasonable doubt. Working together, these expert teams navigate all sides of the complex criminal justice system to make New York a safer place.

John Reese, former CIA paramilitary operative, is presumed dead and teams up with reclusive billionaire Finch to prevent violent crimes in New York City by initiating their own type of justice. With the special training that Reese has had in Covert Operations and Finch's genius software inventing mind, the two are a perfect match for the job that they have to complete. With the help of surveillance equipment, they work "outside the law" and get the right criminal behind bars. 

Told from the points of view of both the Baltimore homicide and narcotics detectives and their targets, the series captures a universe in which the national war on drugs has become a permanent, self-sustaining bureaucracy, and distinctions between good and evil are routinely obliterated.

Former Syracuse, New York, police detective Carrie Wells has hyperthymesia, a rare medical condition that gives her the ability to visually remember everything. She reluctantly joins the New York City Police Department's Queens homicide unit after her former boyfriend and partner asks for help with solving a case. The move allows her to try to find out the one thing she has been unable to remember, which is what happened the day her sister was murdered.

Out on the lacrosse pitch, wealthy but troubled Jesse and poor but driven Tosha form an easy and deep bond, but their relationship is threatened once they enter the hallways of an elite prep school they attend in Washington, D.C. There, they must work to overcome racial and other tensions in their classmates, and in themselves, if they hope to keep their friendship alive.

Police informant Raffy-el thinks he's gotten the upper hand on cops and crooks alike when he obtains a master list of all the snitches the Philadelphia police have working for them. Instead, he discovers he's been played. Now he and his brother, Salim, must elude the corrupt cops and fellow criminals who are hunting them down.