Mike Sullivan works as a hit man for crime boss John Rooney. Sullivan views Rooney as a father figure, however after his son is witness to a killing, Mike Sullivan finds himself on the run in attempt to save the life of his son and at the same time looking for revenge on those who wronged him.

A distant, slightly dysfunctional family is brought closer together when the father's long-estranged Uncle Nino comes from Italy to Chicago for a surprise visit.

Hannah and Rachel grew up as little girls in the same small Midwest town, where traditional gender expectations eventually challenge their deep love for one another.