A director of a low budget movie decides to kill her fellow cast and crew members as they have used her art to become rich and famous.

After winning an all-expenses-paid Mardis Gras vacation in New Orleans, a tight-knit group of college friends prepare for the time of their lives. But boobs, beads and debauchery get pushed to the back burner when murder bubbles up to the surface. A local tourist trap hawking voodoo trinkets seems to be the source of all the trouble, but no one's sure who's pulling the strings when it comes to orchestrating the killings.