Steve McGarrett returns home to Oahu, in order to find his father's killer. The governor offers him the chance to run his own task force (Five-0). Steve's team is joined by Chin Ho Kelly, Danny "Danno" Williams, and Kono Kalakaua.

Dr. Beaumont Rosewood, Jr. is a brilliant private pathologist who uses wildly sophisticated technology and his drive to live life to the fullest to help a tough-as-nails detective and the Miami PD uncover clues no one else can see.

Infatuated with the hottest girl in school, fifth-grader Cameron Sawyer puts everything on the line – including his mullet – to win the girl of his dreams.