Under a powerful Mayan curse, snakes are hatched inside a young woman, slowly devouring her from within. Her only chance for survival is a powerful shaman who lives across the border. With only hours to live, she jumps on a train headed for Los Angeles. Unfortunately for the passengers aboard, they are now trapped, soon to be victims of these flesh-eating vipers.

Chuck Peterson is a young slacker with big dreams. Disowned by his family and ignored by his peers, he diligently pursues his dreams of writing a fantastic children's book to become famous and strike it rich. But due to a bipolar disorder and lack of creative talent, he slums his way through life relying on small time scams to keep himself afloat. When his gangster roommate makes him an offer he can't refuse, Chuck immediately takes the chance to clear himself of all his debts. But things go from bad to worse when the plan makes Chuck a prime murder suspect among a plethora of pornographers and terrorists!

When a series of haunting murders plagues a small Texas town, law officers Tex Holland and Pike McGraw lead the investigation. The murders turn out to be the most shocking and vile acts of sadism to ever hit the once peaceful community. With a dangerous killer on the loose re-enacting slave punishment on his victims, the cops must face their own personal demons as the murder spree throws them into a dangerous world of mercenary hillbillies and inbred cannibals.