Giulio is a widower, struggling to raise three sons, Marco, Rudi, and Mimmo, as best he can. He lives in Rome's working-class Garbatella neighborhood and runs a wine shop with his two brothers. Lucia, meanwhile, comes from Milan's middle-class background; she's divorced and trying to rebuild her life with her two daughters, Eva and Alice. The two meet by chance and recognize each other: they had a fling as teenagers, many years earlier. Yet first love is never forgotten, and so Giulio and Lucia find themselves together again. Their meeting, however, changes not only the lives of a man and a woman, but also those of two families as different as could be. Two families who find themselves living under the same roof without even having had the time to get to know each other well.

The Merchant (Harvey Keitel) is a Westerner. A merchant dealing in precious stones from Afganistan and Turkey. He's above suspicion. In truth, the "Stone Merchant" is a Christian convert into Islam. He's rich, cultured, fascinating. Leda (Jane March) is a successful woman who works as Head of the Public Relations for a big company. She's married to Alceo, a professor at the Sapienza University, specialized in the history of terrorist movements. Alceo is on a wheel chair. He lost his legs in the attack to the American Embassy in Nairobi in 1998. Shahid is a terrorist. Now he's planning an attack along the English Channel. Their lives, their destinies cross in Turkey, where Leda and Alceo are on holiday. And the plot will go on to Rome and Turin till the epilogue of the attack on the ferry boat.

Carlo is a doctor that has recently lost his wife. Affected by the loss, he is supported by his family and friends, and, above all, for the love he feels towards his little daughter. And then, one day, he meets Camille.

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An odd couple of contrasting cops: one is a disillusioned veteran, the other young, idealistic and speaks fluent Arabic. Ideal for tailing Khalid (Ahmed Hafiene), who was acquitted but is still suspected of having ties with Al-Qaida. The two cops, who initially can't stand each other, find themselves increasingly in contact with the life and habits of Khalid. As the story goes the suspect catches on to them, but when he begins receiving threats the cops become his bodyguards, his escort. Being nearer to him, and knowing him better, the two cops end up making almost friends with the man. At last it comes out that Khalid is the victim of a legal error. He makes accusations against the Italian's justice, but this leads to his expulsion from Italy. The young policeman undertakes a voyage in search of Khalid, that will lead him to Tunisia, and to some final twists.