Dr. Gregory House, a drug-addicted, unconventional, misanthropic medical genius, leads a team of diagnosticians at the fictional Princeton–Plainsboro Teaching Hospital in New Jersey.

In Tree Hill, North Carolina two half brothers share a last name and nothing else. Brooding, blue-collar Lucas is a talented street-side basketball player, but his skills are appreciated only by his friends at the river court. Popular, affluent Nathan basks in the hero-worship of the town, as the star of his high school team. And both boys are the son of former college ball player Dan Scott whose long ago choice to abandon Lucas and his mother Karen, will haunt him long into his life with wife Deb and their son Nathan.

Looking down on her friends and family isn't a way of life for Mary Alice Young... it's a way of death. One day, in her perfect house, in the loveliest of suburbs, Mary Alice ended it all. Now she's taking us into the lives of her family, friends and neighbors, commenting from her elevated P.O.V.

When a mysterious groupie joins legendary cursed band, "The Dark Knights", a series of unexplained murders derails their comeback tour.

Jared, Kate, Rick, and Jessica find themselves stranded in a wreckage yard after their car breaks down during a drag race. Meanwhile, the sheriff's office receives notice that a convict escaped from a local state prison. As the teenagers mysteriously disappear one by one, the killer grows hungry and the thriller continues to unravel.

A troupe of actors hired for a haunted house attraction soon find that they are working in a true house of horror.

In this in your face comedy, two life long friends explore the new American Dream as they start their own wine business while keeping the focus where it counts: on them.