Lisa's dress is soaked in blood and her coat is loaded with money but she can't remember who she is. Her husband, Arjun, a famous surgeon, tries his best to help her recollect things.

Chinna and Chella, two childhood friends from neighboring families, end up falling in love with each other. Soon, a misunderstanding leads to a rift between them and their families.

Memsahab is a woman-oriented movie with a social message of non-violence. Memsahab is based on the cruel incidents post the 1984 riots that happened in Northern India.