Rain, a young black musical prodigy, finds trouble and heartbreak when she witnesses her sister's murder by gangbangers. In order to protect her daughter, Rain's mother secretly contacts Rain's biological mother, and Rain learns the truth of her parentage: She is the daughter of a white socialite. Sent to live with her wealthy grandmother, Rain adjusts to boarding school life, where her musical talents flourish.

While searching for a "cure all" serum, Dr. Edward Kanopolus, "Dr. K", is being pressured for results by the pharmaceutical company funding the project. With time running out, tragedy and desperation drive him to make decisions that will jeopardize the lives of everyone around him and ultimately unleash a terrifying monster on a killing spree.