In Fox's contribution to the all-star revue cycle of early talkies, showboat singer Margie, hearing that the show is in arrears, goes to New York to gather all of the former stars to stage a minstrel show as a benefit.

Although in love with Virginia Philips, Lew Tyler refuses to be supported by his rich prospective father-in-law, causing her to break the engagement. Thus cast off by Virginia and insulted by her father, Tyler finds distraction in Jessie Winkler, an old friend; and through the efforts of Buzzy, a business partner, Lew and Jessie marry. Their marriage is unsuccessful, and Lew, haunted by the memory of Virginia, seeks forgetfulness in a liaison with Coleen Miles, a neighbor.

Goldwyn produced a 1923 film adaptation of Potash and Perlmutter, and a 1924 sequel called In Hollywood with Potash and Perlmutter. In Partners Again the two are in the automobile industry -- This is a lost Film.