NATO operative Jacques Kristoff (Jean-Claude Van Damme) is summoned into action—on his birthday, no less—to track down Galina Konstantin (Laura Harring), who has stolen an extremely valuable and dangerous top-secret container from the Slovakian Government. Finding Galina doesn't take long, and Jacques must wrap up the mission by returning Galina and the contraband to his superiors by train. Things seem to be going smoothly as Jacques and Galina board the train posing as a couple, but soon all hell breaks loose.

Fifteen deaf patients took part in an experimental clinical trail aimed at hearing restoration. Within days, fourteen of the fifteen participants in the trial become violently psychotic, ultimately taking their lives to stop violent side effects brought on by the treatment. This is the story of the sole survivor of the experiment, Patient #14 - Liza Raines, who participation in the experiment gave her super-normal hearing abilities - particularly, the ability to hear the frequency emitted by the brain when it thinks. When her life is suddenly thrown into jeopardy, Liza is forced to use her ability against those set on covering up the fact that she even existed

A blind street musician, shut off from everything but her music, begins working with a reclusive composer who uses sensual metaphors as teaching tools. Farced with the possibility of regaining her eyesight she fears she will lose her musical inspiration.