ER explores the inner workings of an urban teaching hospital and the critical issues faced by the dedicated physicians and staff of its overburdened emergency room.

U.S. Marshal Sam Gerard is accompanying a plane load of convicts from Chicago to New York. The plane crashes spectacularly, and Mark Sheridan escapes. But when Diplomatic Security Agent John Royce is assigned to help Gerard recapture Sheridan, it becomes clear that Sheridan is more than just another murderer.

Two feuding siblings carrying on a heroic family tradition as Chicago firefighters. But when a puzzling series of arson attacks is reported, they are forced to set aside their differences to solve the mystery surrounding these crimes.

Tommy Riley has moved with his dad to Chicago from a 'nice place'. He keeps to himself, goes to school. However, after a street fight, he's noticed and quickly falls into the world of illegal underground boxing — where punches can kill.

Earl Pilcher Jr. runs an equipment rental outfit in Arkansas, lives with his wife and kids and parents, and rarely takes off his gimme cap. His mother dies, leaving a letter explaining he's not her natural son, but the son of a Black woman who died in childbirth; plus, he has a half brother Ray, in Chicago, she wants him to visit. Earl makes the trip, initially receiving a cold welcome from Ray and Ray's son, Virgil. His birth mother's sister, Aunt T., an aged and blind matriarch, takes Earl in tow and insists that the family open up to him.