Follow the lives of a group of young adults living in a brownstone apartment complex on Melrose Place, in Los Angeles, California.

Theorizing that one could time travel within his own lifetime, Dr. Sam Beckett stepped into the Quantum Leap accelerator and vanished... He woke to find himself trapped in the past, facing mirror images that were not his own and driven by an unknown force to change history for the better. His only guide on this journey is Al, an observer from his own time, who appears in the form of a hologram that only Sam can see and hear. And so Dr. Beckett finds himself leaping from life to life, striving to put right what once went wrong and hoping each time that his next leap will be the leap home.

Dr. Mark Sloan is a good-natured, offbeat physician who is called upon to solve murders.

Thrifty, folksy and cantankerous, Matlock charges a premium for his services but is worth every penny: This renowned attorney, always clothed in his trademark light-gray suit and driving his signature Ford Crown Victoria, has an uncanny knack for finding overlooked clues and exposing murderers in dramatic courtroom scenes.

As America's stock of athletic young men is depleted during World War II, a professional all-female baseball league springs up in the Midwest, funded by publicity-hungry candy maker Walter Harvey. Competitive sisters Dottie Hinson and Kit Keller spar with each other, scout Ernie Capadino and grumpy has-been coach Jimmy Dugan on their way to fame.

Harry Crumb is a bumbling and inept private investigator who is hired to solve the kidnapping of a young heiress which he's not expected to solve because his employer is the mastermind behind the kidnapping.

A man's family comes for his 77th birthday and while he loves all of his children and their children, he and his children don't exactly connect. However, he connects with his grandchildren. And he tells them what he wants for his birthday and they do what they can to give it to him.

When East German Eric Brogar wins a gold medal in the pentathlon, he escapes to freedom in the west with the help of a beautiful American athlete. But his demanding coach, Heinrich Mueller vows revenge and Eric's best friend and his father pay the ultimate price for his freedom when they are killed by the Secret Police. In Los Angeles, Eric starts to train for the gold again. But when Mueller comes to America, Eric must win the most deadly game of all… the fight for his life.

Czech refugee Krystyna travels to New York in search of her actress idol and fellow expatriate, Anna. After her own arrival in the Big Apple, Anna finds that celebrity often doesn't travel well, and she must go through a battery of humiliating auditions to try and get work in her adopted land. But when Krystyna and Anna finally meet, they provide a support structure for each other.

A student-teacher relationship goes way beyond the classroom, including pre-historic times.

Kelly, a successful career woman and single mother, and her friend Evelyn are both in search of the ideal man. Kelly eventually finds herself torn between sophisticated art dealer Thomas and struggling writer Jonathan, while Evelyn continues her quest for a flesh and blood version of Michelangelo's "David". But will either woman find the happiness they are seeking?

Tijuana is a mystical city and the scene of different stories, where the characters search for meaning in their lives.