This documentary examines ayahuasca shamanism near Iquitos (a metropolis in the Peruvian Amazon), and the tourism it has attracted. The filmmakers talk with two ayahuasqueros, Percy Garcia and Ron Wheelock, as well as ayuahuasca tourists and local people connected with the ayahuasca industry.

Filmed in the jungles of Peru, shaman Don Jose Campos introduces the practices and benefits of Ayahuasca, the psychoactive plant brew that has been used for healing and visionary journeys by Amazonian shamans for at least a thousand years.