Focuses on a group of toddlers, most prominently Tommy, Chuckie, Phil, Lil, and Angelica, and their day-to-day lives, usually involving common life experiences that become adventures in the babies' imaginations. Adults in the series are almost always unaware of what the children are up to; however, this only provides more room for the babies to explore and discover their surroundings.

Four friends, annoyed at how almost everyone else they know is having sex but them, agree to do what they can to help each other lose their virginity before the end of the summer. Most of their opportunities are foiled by their inexperience and bad planning. Michael, the most sensible boy of the foursome, really just wants to stay with his long-time girlfriend and take their relationship to an intimate level, but after putting him off for six months he grows impatient and splits up with her to seek his fortune elsewhere.