From murder and espionage to terrorism and stolen submarines, a team of special agents investigates any crime that has any connection to Navy and Marine Corps personnel, regardless of rank or position.

When they were boys, Sam and Dean Winchester lost their mother to a mysterious and demonic supernatural force. Subsequently, their father raised them to be soldiers. He taught them about the paranormal evil that lives in the dark corners and on the back roads of America ... and he taught them how to kill it. Now, the Winchester brothers crisscross the country in their '67 Chevy Impala, battling every kind of supernatural threat they encounter along the way.

Dr. Gregory House, a drug-addicted, unconventional, misanthropic medical genius, leads a team of diagnosticians at the fictional Princeton–Plainsboro Teaching Hospital in New Jersey.

In Tree Hill, North Carolina two half brothers share a last name and nothing else. Brooding, blue-collar Lucas is a talented street-side basketball player, but his skills are appreciated only by his friends at the river court. Popular, affluent Nathan basks in the hero-worship of the town, as the star of his high school team. And both boys are the son of former college ball player Dan Scott whose long ago choice to abandon Lucas and his mother Karen, will haunt him long into his life with wife Deb and their son Nathan.

The show follows Crime Scene Investigators working for the Miami-Dade Police Department as they use physical evidence, similar to their Las Vegas counterparts, to solve grisly murders. The series mixes deduction, gritty subject matter, and character-driven drama in the same vein as the original series in the CSI franchise, except that the Miami CSIs are cops first, scientists second.

Four egocentric friends run a neighborhood Irish pub in Philadelphia and try to find their way through the adult world of work and relationships. Unfortunately, their warped views and precarious judgments often lead them to trouble, creating a myriad of uncomfortable situations that usually only get worse before they get better.

The Philadelphia homicide squad's lone female detective finds her calling when she is assigned cases that have never been solved. Detective Lilly Rush combines her natural instincts with the updated technology available today to bring about justice for all the victims she can.

The series follows the ventures of a Missing Persons Unit of the FBI in New York City.

In the fictional town of Neptune, California, student Veronica Mars progresses from high school to college while moonlighting as a private investigator under the tutelage of her detective father.

The high commander of an alien expedition lands on Earth -- what he considers to be the least-important planet -- in human form as Dick Solomon. Along for the ride are his alien compatriots Harry, Sally and Tommy -- who is the eldest of the group but is now angrily trapped in a teen's body.

90210 revolves around several students at the fictional West Beverly Hills High School, including new Beverly Hills residents Annie Wilson and Dixon Wilson. Their father, Harry Wilson, has returned from Kansas to his Beverly Hills childhood home with his family to care for his mother, former television and theater actress Tabitha Wilson, who has a drinking problem and clashes with his wife Debbie Wilson. Annie and Dixon struggle to adjust to their new lives while making friends and yet adhering to their parents' wishes.

The coming of age events and everyday life-lessons of Cory Matthews, a Philadelphian who grows up from a young boy to a married man.

Right out of high school, Sean Finnerty got his girlfriend Claudia pregnant. Now she’s his wife, and at just 32, he’s somehow found himself with 14-year-old daughter Lily, two little boys, and a constant struggle between his need to be responsible and his desperate desire to be irresponsible. His judgmental father Walt and devil-may-care brother Eddie are no help at all. When they all get together, stories always start to fly. Of course, Sean’s family will never let him finish a story; they interrupt, they debate, they derail, they defend themselves; just like any good family would.

Six friends grow and learn at Bayside High.

Detectives Nick O'Malley and Kate Benson work in Special Unit 2, a secret precinct of the Chicago Police Department whose sole charge is to protect the city's citizens from Links, a malicious paranormal species that is the missing link between man and beast.

Fifteen years after the events of the feature film, Kyle Craig is assigned to go undercover in an elite squad of the LAPD as Detective Frank Rourke’s trainee to spy on him and report on his off-book methods. As Frank starts teaching his principled trainee the way of the streets, they form an uneasy alliance that will change the course of both their lives irrevocably.

After his mother's death, Jed Perry and his father move to northern California, where Jed enrolls at Evergreen Academy. Along with Jed, only two other boys attend the formerly all-girls school.

Shipwrecked castaways stumble upon the mysterious island of Caprona in the Bermuda Triangle, confronting man-eating dinosaurs and a stranded German U-Boat crew while trying to escape.

Two childhood friends from South Boston turn to crime as a way to get by, ultimately causing a strain in their personal lives and their friendship.

Teenager Nate Palmer becomes part of his late futurist father's mind-altering experiments and gets recruited by a secret organization to protect revolutionary brain technology.