Dr. Gregory House, a drug-addicted, unconventional, misanthropic medical genius, leads a team of diagnosticians at the fictional Princeton–Plainsboro Teaching Hospital in New Jersey.

After a serial killer imitates the plots of his novels, successful mystery novelist Richard "Rick" Castle receives permission from the Mayor of New York City to tag along with an NYPD homicide investigation team for research purposes.

John Reese, former CIA paramilitary operative, is presumed dead and teams up with reclusive billionaire Finch to prevent violent crimes in New York City by initiating their own type of justice. With the special training that Reese has had in Covert Operations and Finch's genius software inventing mind, the two are a perfect match for the job that they have to complete. With the help of surveillance equipment, they work "outside the law" and get the right criminal behind bars. 

Newlywed Melinda Gordon tries to help the dead communicate with loved ones, but sometimes the messages she receives are intense and confusing. Most of Melinda's efforts involve resolving conflicts that are preventing the spirits from passing over.

The series follows the ventures of a Missing Persons Unit of the FBI in New York City.

When Buy More computer geek Chuck Bartowski unwittingly downloads a database of government information and deadly fighting skills into his head, he becomes the CIA's most vital secret. This sets Chuck on a path to become a full-fledged spy.

Earth is visited by an alien species that threatens humanity's existence. Events unfold in real time through the eyes of five ordinary people across the globe as they struggle to make sense of the chaos unraveling around them.

The detectives of the Organized Crime Control Bureau work to dismantle New York City's most vicious and violent illegal enterprises.

A covert team of special forces operatives risk their lives on undercover missions around the globe, while their wives maintain the homefront, protecting their husbands' secrets.

A newly divorced mom falls down a dangerous rabbit hole of blackmail, murder, and youth soccer.

A detective in a small Pennsylvania town investigates a local murder while trying to keep her life from falling apart.

Follows Andy, who needs to hook up with a hottie, pronto, because he hasn't had sex in... well, forever - and his luck isn't the only thing that's hard. His equally horny teenage roommates also need it superbad, and with the help of their nerdy pal, McAnalovin' and his fake I.D., they may tap more than just a keg.

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Angel is released from juvenile detention on the eve of her 18th birthday. Haunted by her past, she embarks on a journey with her 10 year-old sister that could destroy their future.

A rebellious teenager is sent to a therapeutic boarding school with controversial methods where the treatment of a fellow classmate on his first day makes the consequences of his actions frighteningly clear.

Within a family of doctors, the parents and the adult children find themselves successful professionally but dysfunctional personally. When the patriarch ends up on the brink of death, however, they rally to bring him back from the edge. Then they wield their collective power to extract some changes from him.

A girl learns the brutal sacrifices it takes to satisfy her love.

A lesbian couple takes a mini vacation to repair their relationship, unaware the apartment they rented online may lead to their untimely end.