Tina and Lea are best friends who are also avid fans of Vilma Santos. They were inseparable until Lea decides to leave the country and go to Korea. They promise that someday they will really become one big happy family when their children get married. Years after, by virtue of an old vow, Lucky Girl and Lucky Boy are forced to be together by their mothers. Problem is, they hate each other's guts. But, just when they're falling for each other, love plays a trick on the meddling moms which threatens to bring the young lovers apart.

Three advertising executives are doomed to perpetually look for the right man. Tates, Katie and Sonia are all are stuck in a rut with love, sex and marriage. Tates will do whatever it takes to just to have the man she wants even if he is tangled in a messy annulment case and even if it takes her to shed a lot of money to have him. Katie found her love story with a macho dancer but is scared to let her friends know because of his unconventional job. So she tries to give him a more decent look for her friends to see. She also finds bodily insecurities because of her chubby physique. Sonia is the two-timing chick that finds her self pregnant while being with two men. She is in-love with a painter but finds more security with a rich man. Despite her strong feelings for the former, she chooses to be with the latter in order to provide better for her and her child.

While trying to cozy up to the sexy and mysterious Mina, who recently moved into the boardinghouse above his shop, unlucky Xerox operator Lito is unwittingly placing his life in grave danger.

Venus and Mars are neighbors born during a rare planetary alignment, but while Venus grows up blessed by good fortune, Mars seems destined to bring nothing but bad luck to his friends and family. Just when everything looks hopeless for Mars, he discovers he has a rare gift and also that he's in love with the beautiful Venus. Is romance in the stars for Mars, or will his rotten fate break his heart again?