Raymond "Red" Reddington, one of the FBI's most wanted fugitives, surrenders in person at FBI Headquarters in Washington, D.C. He claims that he and the FBI have the same interests: bringing down dangerous criminals and terrorists. In the last two decades, he's made a list of criminals and terrorists that matter the most but the FBI cannot find because it does not know they exist. Reddington calls this "The Blacklist". Reddington will co-operate, but insists that he will speak only to Elizabeth Keen, a rookie FBI profiler.

A young programmer, Elliot, suffers from a debilitating anti-social disorder and decides that he can only connect to people by hacking them. He wields his skills as a weapon to protect the people that he cares about. Elliot finds himself in the intersection between a cybersecurity firm he works for and the underworld organizations that are recruiting him to bring down corporate America.

Notorious serial killer Joe Carroll, after being found guilty of murdering 14 female students on the Virginia college campus where he taught literature, escapes from death row. The FBI calls former agent Ryan Hardy to consult on the case, as he was the one responsible for Carroll’s capture in 2003. Ryan, working closely with an FBI team, including Mike Weston and FBI Specialist Debra Parker, piece together the ever-growing web of murders orchestrated by the devious Carroll.

'I can shoot ink out of my fingers. That's about it really. Sometimes, in pressure situations, I can shoot it out of my toes.' When Squid Man gets downsized out of the Superhero Society, he's forced to crash on the couch of his former sidekick (and only friend) Warren. Now he spends his time boozing in a dead end bar, reminiscing about the days when the hero groupies were plentiful and even a second-rater like him could sometimes save the universe. But when a reporter wants to include him in an upcoming book about superheroes, Squid Man is forced to face the dark mysteries of his past... and the even more unsettling idea that he might actually have a future.

Strange things start to happen to Jill when she breaks up with her boyfriend of the past few months. The phone keeps ringing but there's no one there, she sees strange messages on her TV screen, and a strange teenage girl is hanging around her home. Is it all a campaign of harassment by her ex boyfriend--or is it something more?