When they were boys, Sam and Dean Winchester lost their mother to a mysterious and demonic supernatural force. Subsequently, their father raised them to be soldiers. He taught them about the paranormal evil that lives in the dark corners and on the back roads of America ... and he taught them how to kill it. Now, the Winchester brothers crisscross the country in their '67 Chevy Impala, battling every kind of supernatural threat they encounter along the way.

Shaun Murphy, a young surgeon with autism and savant syndrome, relocates from a quiet country life to join a prestigious hospital's surgical unit. Unable to personally connect with those around him, Shaun uses his extraordinary medical gifts to save lives and challenge the skepticism of his colleagues.

A medical student who becomes a zombie joins a Coroner's Office in order to gain access to the brains she must reluctantly eat so that she can maintain her humanity. But every brain she eats, she also inherits their memories and must now solve their deaths with help from the Medical examiner and a police detective.

After an experimental gene therapy turns them into monsters, three twenty-somethings band together to hunt down the scientist responsible and force him to make them human again.

When a college student is found dead, English professor Amy uses her crime fiction expertise to unravel the case faster than detective Travis, who ends up working with Amy to catch the killer.

An interior designer brings new life to the house of a widower and his daughter and finds love in the process.

Five guests are mysteriously invited to an inn to celebrate Christmas. With the help of the owner Ben, Sarah discovers that an event from the past may connect them and change their lives forever.

Talia and her childhood best friend Anderson unexpectedly reunite in a curiously familiar looking town full of Christmas spirit that restores its visitors when they need it most.

Natalie tries to bring feuding neighbors together in her new condo building. Her unexpected ally is the building's super who prefers to avoid getting involved.