Drug lord Alonso Marroquín escapes from a Mexican prison in an attempt to go into hiding. A US military secret experiment goes wrong and the elite unit from the Mexican Police that is after Marroquín gets infected, creating a new zombie species. The Army and the zombies end up at the drug lord’s hideout and a battle for human survival begins.

When her mother suddenly disappears with no one to care for her, young Estrella ends up on the street and joins a gang of children, triggering a dangerous and tragic chain of events.

This is the story of Fatima and Diego, siblings who have been left alone and live in a pre-apocalyptic world due to water scarcity, where only the wealthy have access to it.