Raymond "Red" Reddington, one of the FBI's most wanted fugitives, surrenders in person at FBI Headquarters in Washington, D.C. He claims that he and the FBI have the same interests: bringing down dangerous criminals and terrorists. In the last two decades, he's made a list of criminals and terrorists that matter the most but the FBI cannot find because it does not know they exist. Reddington calls this "The Blacklist". Reddington will co-operate, but insists that he will speak only to Elizabeth Keen, a rookie FBI profiler.

A female serial killer who killed four young girls is sent away to prison, but a fifth victim escaped with her life. Twenty years later, the killer escapes and begins hunting for the one who got away.

A father and son unknowingly sleep with the same woman, then four years later compete over the paternity of a child either of them could be the father of.

A beleaguered singing telegramist is stuck performing humiliating telegrams for his eccentric clients until one customer forces him to wake up and face the music.

The love of two young artists is put to the test when unsympathetic adults force the couple into isolation.

Two inmates form an unlikely connection in prison, using Nora Ephron and their imaginations to create an escape.

Sandy, a young, recovering alcoholic, is forced to make amends with her estranged family after a drunk driving accident leaves her sister paralyzed. But when tensions flare and rifts are further divided, Sandy must confront the buried family secret that tore them apart.

A mentally-disturbed aspiring actor returning to New York City discovers the world of social media and faces the horrifying power of the Internet.