A Las Vegas team of forensic investigators are trained to solve criminal cases by scouring the crime scene, collecting irrefutable evidence and finding the missing pieces that solve the mystery.

Six young people from New York City, on their own and struggling to survive in the real world, find the companionship, comfort and support they get from each other to be the perfect antidote to the pressures of life.

After a serial killer imitates the plots of his novels, successful mystery novelist Richard "Rick" Castle receives permission from the Mayor of New York City to tag along with an NYPD homicide investigation team for research purposes.

The show follows Crime Scene Investigators working for the Miami-Dade Police Department as they use physical evidence, similar to their Las Vegas counterparts, to solve grisly murders. The series mixes deduction, gritty subject matter, and character-driven drama in the same vein as the original series in the CSI franchise, except that the Miami CSIs are cops first, scientists second.

Adrian Monk was once a rising star with the San Francisco Police Department, legendary for using unconventional means to solve the department's most baffling cases. But after the tragic (and still unsolved) murder of his wife Trudy, he developed an extreme case of obsessive-compulsive disorder. Now working as a private consultant, Monk continues to investigate cases in the most unconventional ways.

Into every generation a slayer is born: one girl in all the world, a chosen one. She alone will wield the strength and skill to fight the vampires, demons, and the forces of darkness; to stop the spread of their evil and the swell of their number. She is the Slayer.

Deputy Police Chief Brenda Leigh Johnson transfers from Atlanta to LA to head up a special unit of the LAPD that handles sensitive, high-profile murder cases. Johnson's quirky personality and hard-nosed approach often rubs her colleagues the wrong way, but her reputation as one of the world's best interrogator eventually wins over even her toughest critics.

Follow the investigations of a team of NYPD forensic scientists and police officers identified as "Crime Scene Investigators".

Charlie is a non-traditional therapist specializing in anger management. He has a successful private practice and he performs pro bono counseling for an inmate group at a state prison. Prior to his career as a therapist, he was a major league baseball player whose career was put on the shelf for good by his own struggle with anger issues.

Joey has struck out on his own and moved to Hollywood, hoping to truly make it as an actor. Joey says goodbye to a time when his friends were his family and welcomes the chance to turn his family into his friends. After reuniting with his high-strung sister Gina, a strong and sexy hairdresser, Joey moves in with her genius 20-year-old son, graduate student Michael, who literally is a rocket scientist. What Joey lacks in book smarts, however, he more than makes up for with his people skills, making him the best new friend his nephew could ask for.

In an elegant Spanish-style apartment building in the trendy Melrose neighborhood of Los Angeles, a diverse group of 20-somethings have formed a close-knit surrogate family. However, when a bloody body is found floating in the courtyard pool, the police soon discover that almost everyone had a reason to want the deceased out of the way.

When an exclusive clique of teenage socialites accidentally murder their best friend on the morning of her birthday, the three girls responsible conspire to hide the truth.

Wünderkind author Mike Dolan achieved literary fame at age 21 with a steamy exposé on his seemingly idyllic Maine town. Six years later, he hasn't written another word and reluctantly returns home in search of an antidote... where he is welcomed back with all the warmth of a lynch mob and where various odd and unpleasant occurrences are happening.

In this series, E! lists 101 of the most significant moments in certain aspects of entertainment, from celebrity couplings to major public gaffes. Actors, comedians and "experts" from the field of entertainment provide commentary throughout each countdown. Each countdown takes place over the course of five nights.

Molly Kagan, the ex-wife of a Hollywood entertainment mogul, transitions into a fabulous independent life after her divorce.

A fashion industry titan protects her company and reputation from her ruthlessly ambitious rival who will do whatever it takes to win.

A mentally disturbed young woman takes a job at a posh country club and falls in with a clique of wealthy college kids where she's taken under the wing of the clique's twisted leader, who harbors some dark secrets too terrifying to tell.

A new drug promises out-of-body experiences, but users are coming back changed forever, and an otherworldly invasion of Earth is underway.

After being charged with hacking into the Pentagon security system, computer-whiz Josh Martin is kidnapped during house arrest and delivered to a shadowy criminal known as Charles Keller. Requested to hack into the state’s highly advanced electrical system and shut it down, it’s clear what Keller wants—total chaos. When California goes dark, he gets what he wants. And tonight, no one will be prepared for what’s about to happen.

Eddie James, a disgruntled actor who wants to do more than play "Mulligan the Rabbit" on a children's TV show, discovers life can change in a heartbeat when he accidentally gets into a car accident with single mother Annie Baker. In the unexpected friendship that develops between them, Eddie tries to help Annie's nearly-blind daughter Taylor get an operation to restore her sight.