Four Star Playhouse is an American television anthology series that ran from 1952 to 1956, sponsored in its first bi-weekly season by The Singer Company; Bristol-Myers became an alternate sponsor when it became a weekly series in the fall of 1953. The original premise was that Charles Boyer, Ida Lupino, David Niven, and Dick Powell would take turns starring in episodes. However, several other performers took the lead from time to time, including Ronald Colman and Joan Fontaine. Blake Edwards was among the writers and directors who contributed to the series. Edwards created the recurring character of illegal gambling house operator Willie Dante for Dick Powell to play on this series. The character was later revamped and spun off in his own series starring Howard Duff, then-husband of Lupino. The pilot for Meet McGraw, starring Frank Lovejoy, aired here, as did another episode in which Lovejoy recreated his role of Chicago newspaper reporter Randy Stone, from the radio drama Nightbeat.

Kris Kringle, seemingly the embodiment of Santa Claus, is asked to portray the jolly old fellow at Macy's following his performance in the Thanksgiving Day parade. His portrayal is so complete that many begin to question if he truly is Santa Claus, while others question his sanity.

An insurance representative is seduced by a dissatisfied housewife into a scheme of insurance fraud and murder that arouses the suspicion of his colleague, a claims investigator.

An arrogant reporter exploits a story about a man trapped in a cave to revitalize his career.

Walter Burns is an irresistibly conniving newspaper publisher desperate to woo back his paper’s star reporter, who also happens to be his estranged wife. She’s threatening to quit and settle down with a new beau, but, as Walter knows, she has a weakness: she can’t resist a juicy scoop.

After the death of a United States Senator, the idealistic Jefferson Smith is appointed as his replacement in Washington. The naive and earnest new senator soon finds himself battling political corruption.

A husband and wife detective team takes on the search for a missing inventor and almost get killed for their efforts.

Gabby, the waitress in an isolated Arizona diner, dreams of a bigger and better life. One day penniless intellectual Alan drifts into the joint and the two strike up a rapport. Soon enough, notorious killer Duke Mantee takes the diner's inhabitants hostage. Surrounded by miles of desert, the patrons and staff are forced to sit tight with Mantee and his gang overnight.

England, 1763. After being convicted of a crime, the young and beautiful Abigail Hale agrees, to escape the gallows, to serve fourteen years as a slave in the colony of Virginia, whose inhabitants begin to hear and fear the sinister song of the threatening drums of war that resound in the wild Ohio valley.

When transplanted Texan Bob Seton arrives in Lawrence, Kansas he finds much to like about the place, especially Mary McCloud, daughter of the local banker. Politics is in the air however. It's just prior to the civil war and there is already a sharp division in the Territory as to whether it will remain slave-free. When he gets the opportunity to run for marshal, Seton finds himself running against the respected local schoolteacher, William Cantrell. Not is what it seems however. While acting as the upstanding citizen in public, Cantrell is dangerously ambitious and is prepared to do anything to make his mark, and his fortune, on the Territory. When he loses the race for marshal, he forms a group of raiders who run guns into the territory and rob and terrorize settlers throughout the territory. Eventually donning Confederate uniforms, it is left to Seton and the good citizens of Lawrence to face Cantrell and his raiders in one final clash.

Buffalo Bill and Wild Bill Hickok join forces to establish a mail route that can get mail from St. Joseph, Missouri, to Sacramento, California, in ten days. Along the way they must battle bad weather, hostile Indians and outlaws intent on robbing the mail and shutting down the entire operation.

Successful movie director John L. Sullivan, convinced he won't be able to film his ambitious masterpiece until he has suffered, dons a hobo disguise and sets off on a journey, aiming to "know trouble" first-hand. When all he finds is a train ride back to Hollywood and a beautiful blonde companion, he redoubles his efforts, managing to land himself in more trouble than he bargained for when he loses his memory and ends up a prisoner on a chain gang.

Youthful Father Chuck O'Malley led a colorful life of sports, song, and romance before joining the Roman Catholic clergy. After being appointed to a run-down New York parish, O'Malley's worldly knowledge helps him connect with a gang of boys looking for direction, eventually winning over the aging, conventional Parish priest.

Popular mailcoach driver Uncle Willie is in fact in league with the town's crooked banker. They plan to have the bank robbed after emptying it, and when Willie's choice for this doesn't show in time, he gets some local boys to do it. When his man does turn up he decides to stick around, as he is pals with the sheriff and also takes a shine to Willie's daughter Allison. This gives the bad men several new problems.

Wild Bill Hickok, Calamity Jane, and Buffalo Bill go up against Indians and a gunrunner.

In the 1840s, Ramsey MacKay, the driver for the struggling Wells Fargo mail and freight company, will secure an important contract if he delivers fresh oysters to Buffalo from New York City. When he rescues Justine Pryor and her mother, who are stranded in a broken wagon on his route, he doesn't let them slow him down and gives the ladies an exhilirating ride into Buffalo. He arrives in time to obtain the contract and is then sent by company president Henry Wells to St. Louis to establish a branch office.

An elderly couple are forced to separate themselves from each other after their children refuse to take both into one house.

Two attractive jewel thieves, one female (Olympe Bradna), one male (Gene Raymond) escape together after their latest escapade and hide out in the home of an aged concert pianist (Lewis Stone). To cover their tracks and keep the old man from turning them in, the thieves pretend to arrange his comeback concert. The artifice becomes reality, the pianist makes a triumphant return, and the thieves reform. This 1938 film is not a remake of 1932's Stolen Heaven, which wove an entirely different story about a suicide pact.

Phoebe Titus is a tough, swaggering pioneer woman, but her ways become decidedly more feminine when she falls for California bound Peter Muncie. But Peter won't be distracted from his journey and Phoebe is left alone and plenty busy with villains Jefferson Carteret and Lazarus Ward plotting at every turn to destroy her freighting company. She has not seen the last of Peter, however.

A true story about Louis Pasteur, who revolutionized medicine by proving that much disease is caused by microbes, that sanitation is paramount and that at least some diseases can be cured by vaccinations.