The show follows Crime Scene Investigators working for the Miami-Dade Police Department as they use physical evidence, similar to their Las Vegas counterparts, to solve grisly murders. The series mixes deduction, gritty subject matter, and character-driven drama in the same vein as the original series in the CSI franchise, except that the Miami CSIs are cops first, scientists second.

A young woman, Eve, fights back and manages to escape a malicious abductor. However, after discovering she may not be the only victim, Eve unravels a darker truth and decides to turn the tables on her captor.

A married couple, Thomas and Ariana Mitchell are struggling to get pregnant, and is suddenly faced with an even bigger obstacle. A life and death tale that examines God and our relationship with him through the best of times and the darkest times.

Margaret and Martin Harper, both sixty years old, are filing for divorce, but plan to keep everything as civilized as possible. Complications arise when their respective attorneys, the equally cynical Emily Bennett and Kenton Rhodes, unexpectedly fall in love, throwing an extra kink into the proceedings both in and out of the courtroom.

A struggling Asian American Theater company decides to put on a production of Gilbert & Sullivan's The Mikado.