Every Tuesday night, radio talk show host Stevie Bricks invites his listeners to call in and share their stories. When one night he asks people to share the worst thing they’ve ever done, high school teacher Ron Welz can't resist. Big mistake—what he reveals sets off a chain of hilariously uncontrollable events adversely affecting his marriage and another couple. And when someone starts sending him body parts, his life really begins to fall apart. Who is tormenting him? An insolent high school student? His best friend? His wife? There are over eight million people in the Naked City, and everyone's a suspect.

In a single, fully-stocked hotel room on the night of the 2016 general election, two Trump supporters celebrate the unexpected results. As the night rages on, an ensemble of characters venture in and out of the room. Some match the two’s enthusiasm while others voice their terror at the prospect of the incoming president, but most struggle to find reasons to care less about the results that caused the debauched celebration occurring around them.