Dr. Gregory House, a drug-addicted, unconventional, misanthropic medical genius, leads a team of diagnosticians at the fictional Princeton–Plainsboro Teaching Hospital in New Jersey.

A Las Vegas team of forensic investigators are trained to solve criminal cases by scouring the crime scene, collecting irrefutable evidence and finding the missing pieces that solve the mystery.

Looking down on her friends and family isn't a way of life for Mary Alice Young... it's a way of death. One day, in her perfect house, in the loveliest of suburbs, Mary Alice ended it all. Now she's taking us into the lives of her family, friends and neighbors, commenting from her elevated P.O.V.

After a serial killer imitates the plots of his novels, successful mystery novelist Richard "Rick" Castle receives permission from the Mayor of New York City to tag along with an NYPD homicide investigation team for research purposes.

Al Bundy is an unsuccessful middle aged shoe salesman with a miserable life and an equally dysfunctional family. He hates his job, his wife is lazy, his son is dysfunctional (especially with women), and his daughter is dim-witted and promiscuous.

A stand-up comedian and his three offbeat friends weather the pitfalls and payoffs of life in New York City in the '90s. It's a show about nothing.

Set in the charming town of Stars Hollow, Connecticut, the series follows the captivating lives of Lorelai and Rory Gilmore, a mother/daughter pair who have a relationship most people only dream of.

The daily mishaps of a married woman and her semi-dysfunctional family and their attempts to survive life in general in the city of Orson, Indiana.

Adrian Monk was once a rising star with the San Francisco Police Department, legendary for using unconventional means to solve the department's most baffling cases. But after the tragic (and still unsolved) murder of his wife Trudy, he developed an extreme case of obsessive-compulsive disorder. Now working as a private consultant, Monk continues to investigate cases in the most unconventional ways.

In this musical comedy, optimistic high school teacher Will Schuester tries to refuel his own passion while reinventing the high school's glee club and challenging a group of outcasts to realize their star potential as they strive to outshine their singing competition while navigating the cruel halls of McKinley High.

A gifted young teen tries to survive life with his dimwitted, dysfunctional family.

ER explores the inner workings of an urban teaching hospital and the critical issues faced by the dedicated physicians and staff of its overburdened emergency room.

A comedy about a working class Chicago couple who find love at an Overeaters Anonymous meeting.

Follow the lives of a group of teenagers living in the upscale, star-studded community of Beverly Hills, California and attending the fictitious West Beverly Hills High School and, subsequently, the fictitious California University after graduation.

Comedy about the unlikely friendship that develops between two very different young women who meet waitressing at a diner in trendy Williamsburg, Brooklyn, and form a bond over one day owning their own successful cupcake business. Only one thing stands in their way – they’re broke.

Dr. Mark Sloan is a good-natured, offbeat physician who is called upon to solve murders.

Aan irreverent and outrageous take on true family love‐and dysfunction. Newly sober single mom Christy struggles to raise two children in a world full of temptations and pitfalls. Testing her sobriety is her formerly estranged mother, now back in Christy's life and eager to share passive-aggressive insights into her daughter's many mistakes.

Drew is an assistant director of personnel in a Cleveland department store and he has been stuck there for ten years. Other than fighting with co-worker Mimi, his hobbies include drinking beer and not being able to get dates. To make a few extra bucks he has a micro-brewery going in his garage with his buddies.

The daily trials and tribulations of handyman Tim Taylor, a TV show host raising three boys with help from his loyal co-host, domineering wife, and unseen neighbor.

The high commander of an alien expedition lands on Earth -- what he considers to be the least-important planet -- in human form as Dick Solomon. Along for the ride are his alien compatriots Harry, Sally and Tommy -- who is the eldest of the group but is now angrily trapped in a teen's body.