An elite team of FBI profilers analyze the country's most twisted criminal minds, anticipating their next moves before they strike again. The Behavioral Analysis Unit's most experienced agent is David Rossi, a founding member of the BAU who returns to help the team solve new cases.

Chicagoan Frank Gallagher is the proud single dad of six smart, industrious, independent kids, who without him would be... perhaps better off. When Frank's not at the bar spending what little money they have, he's passed out on the floor. But the kids have found ways to grow up in spite of him. They may not be like any family you know, but they make no apologies for being exactly who they are.

Dexter Morgan, a blood spatter pattern analyst for the Miami Metro Police also leads a secret life as a serial killer, hunting down criminals who have slipped through the cracks of justice.

Dr. Temperance Brennan and her colleagues at the Jeffersonian's Medico-Legal Lab assist Special Agent Seeley Booth with murder investigations when the remains are so badly decomposed, burned or destroyed that the standard identification methods are useless.

A father recounts to his children - through a series of flashbacks - the journey he and his four best friends took leading up to him meeting their mother.

The exploits of the Los Angeles–based Office of Special Projects (OSP), an elite division of the Naval Criminal Investigative Service that specializes in undercover assignments.

Three sisters (Prue, Piper and Phoebe) reunite and unlock their powers to become the Charmed Ones, the most powerful good witches of all time, whose prophesied destiny is to protect innocent lives from evil beings such as demons and warlocks. Each sister possesses unique magical powers that grow and evolve, while they attempt to maintain normal lives in modern day San Francisco.

On her sixteenth birthday, Sabrina Spellman discovers she has magical powers. She lives with her 600-year-old aunts Hilda and Zelda as well as talking cat Salem in the fictional town of Westbridge, Massachusetts.

Life’s good for deliveryman Doug Heffernan, until his newly widowed father-in-law, Arthur, moves in with him and his wife Carrie. Doug is no longer the king of his domain, and instead of having a big screen television in his recently renovated basement, he now has a crazy old man.

ER explores the inner workings of an urban teaching hospital and the critical issues faced by the dedicated physicians and staff of its overburdened emergency room.

The series follows the ventures of a Missing Persons Unit of the FBI in New York City.

The Philadelphia homicide squad's lone female detective finds her calling when she is assigned cases that have never been solved. Detective Lilly Rush combines her natural instincts with the updated technology available today to bring about justice for all the victims she can.

Perhaps their strikingly different personalities make the relationship between detective Jane Rizzoli and medical examiner Maura Isles so effective. Jane, the only female cop in Boston's homicide division, is tough, relentless and rarely lets her guard down, while the impeccably dressed Maura displays a sometimes icy temperament — she is, after all, more comfortable among the dead than the living. Together, the best friends have forged a quirky and supportive relationship; they drop the protective shield in each other's company, and combine their expertise to solve Boston's most complex cases.

Ed Deline is a strict ex-CIA officer who went from being Head of Security to becoming President of Operations of the Montecito, whose job is to run the day-to-day operations of the casino. Following his departure, former Marine Danny McCoy, Ed's former protégé, becomes the Montecito's new President of Operations.

The vampire Angel, cursed with a soul, moves to Los Angeles and aids people with supernatural-related problems while questing for his own redemption. A spin-off from Buffy the Vampire Slayer.

The Duncans a European-American family in Colorado is adjusting to the surprise birth of their fourth child, Charlie. When parents Amy and Bob return to work they put their latest addition in the care of her three older siblings, PJ, Teddy, and Gabe. Teens PJ and Teddy and tween brother Gabe are typical kids -- that is, until their mother has another baby. The arrival of their new sister completely upends the entire household. When their mother heads back to work after Charlie's birth, it's up to the kids and their dad to keep the home fires burning -- and to keep Charlie out of trouble as she learns to sit up, crawl, walk and run. Teddy, as the older sister, makes a personalized video diary for Charlie, in each episode adding a nugget of wisdom for her baby sibling.

Felicity Porter, a sensitive and intelligent girl from the San Francisco Bay Area, decides to give up a slot at Stanford University's pre-med program to follow her long time crush to college in New York City. Things get even more complicated when she meets her dorm's resident advisor and they fall in love.

Chris is a teenager growing up as the eldest of three children in Brooklyn, New York during the early 1980s. Uprooted to a new neighborhood and bused to a predominantly white middle school two-hours away by his strict, hard-working parents, Chris struggles to find his place while keeping his siblings in line at home and surmounting the challenges of junior high.

A hit man from the Midwest moves to Los Angeles and gets caught up in the city's theatre arts scene.

Dr. Beaumont Rosewood, Jr. is a brilliant private pathologist who uses wildly sophisticated technology and his drive to live life to the fullest to help a tough-as-nails detective and the Miami PD uncover clues no one else can see.